wpe1.jpg (4875 bytes)How to administer 714X
You are preparing to use a health product commonly known as 714X. This document complements the educational video tape explaining the use of 714X as well as the written technical data sheet describing 714X. This video tape, which visually demonstrates the steps involved in the injection technique as well as the nebulizer usage, may be purchased at CERBE Distribution inc.


Table of contents

Left-handed person
Right-handed person






Introduction

714X is a health product developed by a biologist named Gaston Naessens. 714X is manufactured by the Centre Expérimental de Recherches Biologiques de l'Estrie Inc. and its distribution is assured by CERBE Distribution Inc. This product is specifically designed to stimulate the body's natural defenses. 714X is a product which assists the organism to better defend itself by bringing necessary support to the immune system.

714X has a particular means of operation: it has been designed to directly act upon the lymph, a circulation paralleling the blood stream. This product must be specifically introduced into the lymphatic system so that its mode of action may be accomplished.

Nature has provided the human body with a lymphatic circulation that drains independently two distinct regions of the body (see diagram). These are called the large and the small lymphatic circulation.

As the basic treatment, 714X is introduced into the organism by way of injection into the large lymphatic circulation (that is the one draining the lower part of the body as well as the upper left side of the body).

As a secondary or adjuvant therapy (when required), 714X is absorbed by way of inhalation (see Technical Data). The respiratory tract allows 714X to reach the nodes of the small lymphatic circulation located in the upper right side of the body. To accomplish this, one must use a medical device known as a nebulizer.

Because 714X must be introduced directly into the lymphatic system, it can ONLY BE MADE in liquid form. As opposed to many other medications which are absorbed either through the blood or through the digestive system, 714X, due to its action directly on the lymph, cannot be used in any other forms such as creams, syrups or pills.


Perinodular injection

Here are the five steps of the perinodular injection:

  1. PREPARING THE MATERIAL
  2. PREPARING THE SYRINGE
  3. PREPARING THE PERSON RECEIVING THE INJECTION (FREEZING THE INJECTION SITE)
  4. THE INJECTION ITSELF: PASSIVE INJECTION OR SELF-ADMINISTERED INJECTION
  5. GATHERING THE USED MATERIAL
The basic 714X treatment remains the perinodular injection designed to reach the large lymphatic circulation. The perinodular injection (which literally means in the area of the nodes) is performed in the right groin area.Whether the injection be passive or self administered, it always requires the same material and is to be done according to the same sequence of events.

N.B. : In this document references to passive injection relate to injections being performed by one person on another person. Self-injection refers to a person injecting himself with the product.










Preparing the material

Material needed

As mentioned, the required material should be gathered in one tray.

  • One 6.5 ml vial of 714X. (Note: one cycle requires two vials of product).
  • A 1 cc Tuberculin syringe, graded by 1/100 and a needle having a 26G gage and a 3/8" length.
  • 94 % alcohol (ethyl alcohol often available in Liquor Stores) to be used with an alcohol dispenser in order to reduce waste (never use isopropyl alcohol as it denatures the product).
  • Sterile cotton swabs (cosmetic cotton balls are also convenient) (Do not use isopropyl pre-soaked tampons or cotton balls.)
  • One small frozen "Ice Pak" (or a small plastic bag, "Ziploc" type filled with ice cubes).
  • One box of tissue paper or paper towels.
  • A watch or clock which also displays seconds not only minutes.
  • One alcohol dispenser, if possible, to prevent spilling alcohol.
  • A jar containing a mixture of bleach and water (approximately one litre), to later dispose of used material (needles, syringes, cotton balls, etc.).
  • One hand scrub brush.
Ideally, the material required to perform the daily injection should be gathered in one tray to facilitate the injection routine and avoid spreading out the material. Also, the tray and its content should be stored safely, out of small children's reach, when the injection is completed.

Please note :

  1. Once a vial of 714X has been opened (by removal   of the small metallic cap on top) the product must be kept refrigerated at 39.2 oF (4 oC) (generally the normal temperature of a refrigerator) when not being handled during the preparation of the syringe.  This is to avoid the vaporisation of the camphor contained in the product.

  2. Prior to being opened, as described in the preceding paragraph, vials of 714X can be stored at room temperature in a cool place (or in the refrigerator) up to the expiration date identified on the box containing the product. Once opened, a vial of 714X must be returned to the refrigerator without delay when not being used to fill a syringe. A vial of 714X, once opened, must be used within 25 days of being opened.






Filling the syringe

Prior to undertaking this process, wash your hands with a scrub brush, preferably using an antibacterial soap.


STEP 1 :Preparing the syringe
Use a 1 cc Tuberculin syringe, graded by 1/100 and a needle having a 26G gage and a 3/8" length. Remove the syringe from its sterile packaging by pulling on the tabs at the top of the packaging. Make sure the needle is well fixed to the syringe. Also insure that the needle protector cap slides out easily and that it can be delicately replaced once the filling of the syringe is completed. Pull down on the piston a few times to loosen the mechanism, in order to facilitate the injection.
STEP 2 :Preparing the vial of 714X
Take hold of the vial of 714X (unopened if this is the first use made of it). When using a new vial of 714X, clean the metallic cap with a cotton ball soaked with 94 % alcohol. Dry thoroughly. Lift out the removable portion of the metallic cap. The circular area under the removable portion of the metallic cap will reveal the grey rubber stopper in which you will insert the needle to draw out the required daily quantity of product.

Using a new cotton ball soaked with 94 % alcohol, clean the grey rubber stopper.

STEP 3 :Inserting the needle into the 714X vial - drawing out the product
Take the syringe which has been removed from its packaging. Remove the protective cap. Hold the syringe in the right hand (for right-handed people) or in the left hand (for left-handed people) as if you were holding a pen or pencil. Take the vial of 714X and turn it upside down. Pierce the centre of the grey rubber stopper with the needle attached to the syringe. With the left hand, hold both the vial and the syringe in the inverted vertical position. Slowly pull the piston of the syringe down until the required dosage of 714X has been collected in the syringe. (see Diagram for specified dosages.)

Do not forget to draw an extra 0.1 ml of product into the syringe to compensate for the amount of product which will remain trapped in the head of the syringe.

Example: If 0.5 ml is required, add 0.1 ml for a total of 0.6 ml to be collected in the syringe. The amount of product which will remain trapped in the syringe has been taken into account in the volume of 714X needed for a 21-day treatment (2 X 6.5 ml = 13 ml).

Reminder :

  1. During the first five days of treatment of the first cycle, the product is injected on a gradual basis beginning with 0.1 ml on the first day, 0.2 ml on the second day and so on until day five.
  2. From day five to day twenty-one of the first cycle, a daily dose of 0.5 ml is injected.
  3. Each twenty-one day cycle must be followed by a two day break where no injections are administered.
  4. For each subsequent cycle (second and following), the product is to be injected at a daily dose of 0.5 ml from the first to the last day of the twenty-one day cycle.
  5. Children weighing less than 30 kg (66 pounds) will receive half the daily dose used by adults.
STEP 4 :Removing the filled syringe
Still in the inverted vertical position, remove the needle from the grey rubber stopper of the 714X vial. The vial can then be replaced upright in the tray. Slightly pull down the piston of the syringe and then tap on the syringe so that any air bubbles trapped in the syringe may be moved to the surface of the liquid in the syringe.

Slowly push the piston back up until a drop of 714X appears at the tip of the needle. Do not push too hard on the piston to avoid wasting product.

Replace the protective cap on the needle (without pressing it in too firmly) so that the sterility of the needle is preserved up to the time of the injection.

Notes :
  1. Once the syringe has been filled, do not forget to immediately replace the 714X vial in the refrigerator.
  2. The injection must begin within twenty minutes of the filling of the syringe. If for some reason the injection is delayed, place the syringe in the refrigerator until it is time to begin the injection.





Preparing the person receiving the injection

The injection must be performed in a calm and peaceful setting. An intimate surrounding and a comfortable temperature are also elements that facilitate the injection. The person receiving the injection should choose the room he or she is most comfortable in to receive the injection. For the passive injection, a semi-lying down position is recommended (either on a bed or on a sofa with many pillows). For self-injection, a semi-seated position is desirable (either in a reclining chair or in a bed with several pillows raising the upper body).

In each case, it is better to wear loose fitting underwear that does not inhibit the circulation. It must be easily pulled down for the duration of the injection period. Three steps will prepare the person receiving the injection:

STEP 1 : Cooling down the injection site
This step is very important. The cooling down of the injection site is very important in order to stop the rapid vaporisation of the camphor contained in the product within the tissues of the body. At body temperature (98.6 oF or 37 oC), camphor has a tendency to vaporise. The cooling down of the injection site assures a painless injection and the optimal absorption of the product by the lymphatic system where the product is designed to act.

For both passive and self-injection, the injection site is in the right groin area known as the right inguinal area.


Procedure :
Place an Ice Pack (or a bag filled with ice) on the fold of the right groin area called the crural fold inserting a tissue paper (Kleenex) between the skin and the Ice Pack for hygienic reasons. Leave the ice pack in place for 8 to 10 minutes. The skin should take on a slightly pinkish colour prior to beginning the injection. Should the Ice Pack be difficult to bear with the use of a tissue paper, a paper towel, which is slightly thicker, may be substituted for the tissue paper. Adjustments should be made to deal with each person?s skin sensitivity.
STEP 2 : Disinfecting the injection site
When the skin has been cooled down sufficiently (once it is slightly pink) disinfect the injection site with a cotton ball or swab soaked with 94 % alcohol.

Notes :
  1. At this stage, for the passive injection, it is recommended, for precautionary reasons, that the person giving the injection wear plastic gloves, if the condition being treated is a contagious disease.
  2. For self-injections, where the same conditions are present, it is not necessary to wear plastic gloves.

STEP 3 : How to locate the injection site
The following technique uses an anatomical reference point, the pulse of the femoral artery found in the fold of the right groin area.

The technique to properly locate the injection site is as follows:

  1. With the middle and ring finger of the right hand (for right-handed people) feel the right groin area, in the fold of the leg, to locate a pulsating type motion similar to a cardiac pulse which identifies the femoral artery.

    Take all the time necessary to find this localized pulsating movement. For some people, this pulsating movement is very deep in the fold whereas for others, it is very superficial. Also, some people have this pulse located further up or down the line of the fold of the groin. It is therefore recommended to properly locate this pulsating motion of the femoral artery. Once found, it will be easily located on subsequent attempts. It is usually the first attempt at locating this pulse which may prove arduous.
  2. Once the femoral pulse has been located and to easily identify the injection site, draw an imaginary line between the location of the pulse and the navel.

    For adults, the injection site is located from 3 to 5 cm (1.5 to 2 inches) above the pulse of the femoral artery on an imaginary line drawn between the pulse and the navel.

    For children weighing less than 30 kg (66 pounds), the injection site is located from 1 to 2.5 cm (0.5 to 1 inch) above the pulse of the femoral artery on an imaginary line drawn between the pulse and the navel.

The three deep lymph nodes sought are located in this area. The product injected within the area of these deep nodes will be absorbed by one of these nodes thus the name of perinodular injection.

The injection site has an approximate surface of a small 1 cm circle. The needle does not have to be inserted each day in the same hole created by the needle. It suffices that it be injected in the same area which therefore leaves a certain margin to work with.


Passive injection done by a right-handed person
STEP 1 : Preparation
Once the injection site has been sufficiently cooled down with the use of an ice pack or bag containing ice cubes (approximately eight to ten minutes of application), disinfect the injection area using a cotton swab or ball soaked with 94 % alcohol. Allow the alcohol to dry.
STEP 2 : Localize the injection site
With the middle and ring fingers of the right hand, locate the pulse of the femoral artery located in the right groin area.
STEP 3 :Apply and maintain pressure with these same two fingers
With the side of the left hand firmly stretch the skin of the lower stomach towards the navel. The skin must remain stretched during the entire injection.
STEP 4 :Raising of the deep lymph nodes
While keeping the lower stomach?s skin well stretched, rotate the wrist of the left hand towards the groin so that the thumb of the left hand may replace and continue to apply the pressure previously maintained on the femoral artery by the middle and ring fingers of the right hand. Remove the right hand. The right hand may now be used to handle the syringe and do the injection. The pressure being applied by the thumb of the left hand on the femoral artery must be maintained throughout the injection to uphold the raised position of the deep lymph nodes, target of the perinodular injection.
STEP 5 :Injecting 714X into the lymph
Without any hesitation, using the right hand and a rapid motion, insert the needle into the injection site. To control the flow of solution being injected, it is preferable to activate the piston of the syringe by turning the sides of the piston rather than pushing down on the piston itself. Activate the piston once every ten to fifteen seconds so that the solution is gradually introduced into the lymphatic circulation. The needle itself should remain at a 45o angle with the skin.

When the product has been fully injected, that is when the piston has been pushed in to its maximum depth, allow 60 seconds to elapse prior to removing the needle. This is purely a preventive measure to avoid having the last few drops of product escape through the channel created by the needle. This back flow of product could cause a disagreeable stinging sensation created by the vaporisation of the camphor in the surrounding tissues. Even though the possible stinging sensation is uncomfortable, it is in no way dangerous.
STEP 6 :Cooling the injection site after the injection
Upon removing the needle, immediately disinfect the injection site with a new cotton ball soaked with 94% alcohol. Place the Ice Pack (or the bag of ice) over the right groin area while leaving the cotton ball on the actual injection site to insure sterility of the injection site.

Again, a tissue paper or a paper towel may be placed between the Ice Pack and the skin (but over the cotton ball) to avoid any discomfort caused by the icing down of the area. The cooling period may last anywhere from 5 to 15 minutes according to each person?s situation. Once the cooling down period is completed, the patient may resume normal daily activities. Strenuous physical activity such as intense physical training or contact sports are not recommended for a few hours following the injection period.

The injection site, that is the right inguinal area, remains the same whether the person is right or left handed. Purely anatomical reasons justify this choice. Even a left-handed person must perform the injection in the right inguinal area.


Passive injection done by a left-handed person
The steps for the passive injection being performed by a left-handed person remain the same as the passive injection being performed by a right-handed person with the sole exception being the interplay of the hands when localizing the femoral pulse and maintaining the pressure on the artery. During the injection, the needle is maintained at a 45o angle with the skin. Each step of the protocol must be reread and applied for a left-handed person.

Reminder:

The injection of 714X is always done in the right inguinal area to maximize the draining of the large lymphatic circulation. As has been previously mentioned, the injection site is located from 3 to 5 cm (1.5 to 2 inches) above the right femoral pulse on an imaginary line drawn between the femoral pulse and the navel (see videotapes).
Self-injection done by a right-handed person
Conditions permitting, self-injection is highly recommended. Self-injection offers greater autonomy to the person undertaking 714X therapy which may necessitate several 21 day cycles. Self-injection confirms an individual?s taking charge of his or her own situation. When self-injecting, a person has the liberty to choose the best time to do the injection without depending on someone else?s schedule. From all points of view, self-injection is highly recommended.

Review the steps above dealing with preliminary matters (cooling down the injection site, disinfecting).
STEP 1 : Find the pulse of the femoral artery using the middle and ring fingers of the left hand.
Once the pulse is located, pressure must be maintained on it. Constant pressure needs to be maintained during the entire injection period to insure that the deep lymph nodes remain in a raised position. With the thumb of the left hand, stretch the skin of the lower abdomen towards the navel.
STEP 2 : Performing the injection with the right hand.
Pick up the syringe already prepared to do the injection. Remove the protective cap and hold the syringe as if it were a pen or pencil. The needle should be pointing towards the left side of the body, parallel to the right inguinal fold. When the injection site is found, place the needle at the injection site. Close your eyes and quickly and firmly insert the entire length of the needle (3/8th inch) into the injection site. If the insertion is not done firmly enough, the skin?s natural resistance will slow the penetration of the needle which may cause a disagreeable sensation. If the eyes are kept opened, a natural reflex is to stop inserting the needle once it touches the skin.

While maintaining the pressure on the femoral artery with the middle and ring fingers of the left hand, release the skin being stretched by the left thumb and use the left thumb and left index finger to hold the syringe in place. Gently press down on the piston every 15 to 20 seconds. The solution will then be injected bit by bit. Once the piston has been completely pushed in, the syringe is empty.

Release the pressure on the pulse and wait 60 seconds prior to removing the needle. (This is a precautionary step to prevent the last few drops of 714X from escaping through the channel created by the needle.) After the pause, remove the needle in one quick stroke and immediately disinfect the area.
STEP 3 : Disinfecting and cooling down the injection site - post-injection.
Cover the injection site with a new cotton ball soaked with 94 % alcohol prior to replacing the ice pack on the area. A tissue paper may be inserted between the ice pack and the skin (but over the cotton ball) if necessary. The cooling down period may last between 5 and 15 minutes. Its objective is to insure the best possible distribution of product into the lymphatic system.

Once the cool down period is over, normal daily activities may be resumed. However, as with the passive injection, intense physical activity should be avoided for a few hours.














Self-injection done by a left-handed person
Whether one is left-handed or right-handed, the injection site remains the same, that is the right inguinal area (refer to the step dealing with cooling down the injection area). All steps remain the same for a left-handed person except for the play of hands which is inverted. Locating the femoral pulse is done with the right hand and the injection is subsequently done with the left hand. Reread the protocol for self-injection by a right-handed person and adjust accordingly.

















Gathering the used material
It is highly recommended to use a glass jar which can be hermetically sealed to hold all used material (needles, cotton balls, etc.)

Fill the jar with a mixture of bleach and water (ten parts water and one part bleach). This preventive measure is suggested to avoid any incidents occurring when handling domestic waste products.

Where the person using 714X is suffering from some type of contagious degenerative disease, it is recommended to contact local health authorities to find out what is the proper way to dispose of used biological material (needles, syringes, cotton balls, gloves, etc.). In this way, contamination risks are avoided for those people present in the immediate surroundings.









Particular cases
In certain cases, the injection protocol previously described must be adapted to particular circumstances. Two situations come to mind:

Obese people

    It is preferable for an obese person to receive the help of another person when self-injecting. This other person will assist by holding the skin of the abdominal area in a raised position during the entire injection period. This help will facilitate the locating of the injection site and will free both hands of the person self-injecting to perform the actual injection according to the protocol.

    In such cases, an adjustable mirror fixed to the right of the person self-injecting will facilitate the viewing of the injection site.


Lymph nodes of the groin have been removed

    When the lymph nodes situated in the right groin area have been surgically removed, 714X will need to be injected in the left inguinal area. There simply is no other solution. In such cases, all the preparations leading up to the injection remain the same albeit performed on the left inguinal area: locating the femoral pulse and the injection site, maintaining the pressure on the artery, disinfecting the site, cooling down the area. The injection technique does not change. The needle however will be oriented towards the right side of the body and will aim for the deep lymph nodes of the left side of the body.

    When the lymph nodes have been removed from both sides of the body, it becomes impossible to do perinodular injections of 714X. In such exceptional circumstances, the use of an ultrasonic nebulizer is the only way to administer 714X. (See Section II).

    In this particular circumstance, where 714X can no longer be injected in the large lymphatic circulation as is proposed in the above described protocol, a restricted, but still effective treatment of 714X may be adapted. This treatment is performed by way of a medical device called an ultrasonic nebulizer. 714X will then be inhaled and absorbed through the lymph nodes of the respiratory tract. (See Section II of this protocol).



Practical advice
Whether you self-inject or whether you receive the injection, it is normal to question oneself on the use of the product. Also, since a particular injection technique is being used, it is also normal to question whether the injection was done right given that the product?s effectiveness is related to the success of the injection.

Am I injecting in the right area ?

A painless injection is confirmation that the proper injection site has been found. Following all the steps of the recommended protocol (proper localisation, cool down, etc.) leads to a painless perinodular injection. However in some cases where the patient is affected by some degenerative disease, his or her pain threshold may be lower than other people?s, thus he or she may be more sensitive to pain.

For some people it is quite normal to feel a certain pinching or prickling sensation when the needle pierces the skin. For others this step is totally painless. Once the injection site is well located, we recommend that the eyes be kept shut when actually inserting the needle and that this be done in a quick abrupt motion thus avoiding the hesitation and recoil reflex that may otherwise occur. After just a few days, everyone develops their own expertise on how to insert the needle.

Others again will feel some pressure at the injection site or a slight burning or warming sensation: this can result from either releasing the pressure on the femoral artery or from injecting the product too rapidly. To lessen the burning or warming sensation, simply place the ice pack or bag of ice close to the needle. The feeling of pressure can be relieved in some instances by raising and lowering the skin adjacent to the injection site.

If a strong burning sensation is felt during the first few moments of the injection and the feeling gets progressively worse, the needle is definitely outside the proper injection site. This burning sensation is caused by the vaporisation of the camphor contained in 714X which then irritates the surrounding muscular fibres of the abdominal wall. This situation, however uncomfortable, is not harmful. Should this occur, withdraw the needle without any hesitation, cool down the site for just a few moments and then reinsert the needle in the proper site after having again disinfected the area.

Can the time taken to inject the product be either lengthened or shortened without compromising the integrity of the product ?

Ten to twelve minutes is the injection time recommended by the manufacturer of 714X (excluding the cool down periods). Depending upon each person?s pain threshold, the time to inject may be increased, for example, to twenty minutes or decreased, for example, to five minutes without in any way affecting the efficacy of the product. The variation in the time of injection is quite acceptable and is dependent upon each person?s tolerance. As long as the daily injection is carried out with regularity everyday at about the same time there is no strict rule on the length of time needed to inject. With time, a certain skill level is achieved in the handling of the injection and it becomes easier to execute.


Is it normal to feel a slight burning sensation at the injection site several hours after the injection is completed ?

Most people feel nothing after the injection is completed. Some people may occasionally feel a slight burning sensation after the injection, especially at the very beginning of the treatment. This is neither abnormal nor a bad sign.

As has been mentioned, normal daily activities may be resumed after the injection has been done. However, during the first few hours following the injection, running up stairs, strenuous physical exercise or even taking a hot sauna bath are to be avoided. Should a slight burning sensation occur some hours after the injection has been done, reapply the ice pack or a bag of ice on the affected area and the burning sensation will rapidly disappear.


Is bruising normal at the injection site ?

Certain individuals bruise easier than others. For these people, a bruise may appear at the injection site. After having completed the perinodular injection, when removing the needle, if a drop of blood appears, it is likely that a small bruise will develop at the injection site. This manifestation is not threatening nor will it impede the continuation of the therapy.



Conclusion
People are not generally used to handling syringes and needles. This is a domain generally reserved for medical professionals. This therapy however requires a daily commitment and effort.

Once the perinodular injection technique is mastered, it remains a relatively simple procedure. For most individuals, the procedure is completely painless while for others there may be a slight uncomfortable sensation. In some rare cases, certain people, due to a very low pain threshold, may be more sensitive to the injection. Each individual?s tolerance must be considered and respected.

The suggested injection protocol takes these variables into account and attempts to substantially reduce any discomfort which may accompany the perinodular injection.

As experience is gained in doing the injection or having it performed on oneself, the more agreeable the experience becomes. As has been mentioned previously, one must learn to have confidence in his or her means and to undertake the daily injection as a special time to relax and unwind.






Inhalation of 714X by way of ultrasonic nebulizer
As was previously described in the preceding section, the perinodular injection seeks to drain the large lymphatic circulation (75 % of the body).

The secondary treatment is recommended to reach the small lymphatic circulation which drains the upper right side of the body (25 %).

The addition of the secondary treatment is advisable if the disease affecting the patient is localized in the upper right side of the body.

To reach the small lymphatic circulation, 714X must be absorbed through the lymph nodes present in the upper respiratory tract. This is why a medical device known as an ultrasonic nebulizer must be used in this procedure. This device transforms any liquid product into very fine droplets to be introduced into the organism.
A specifically designed 714X mixture for use in an ultrasonic nebulizer is transformed into vapour and is easily absorbed by the lymph nodes of the respiratory tract.

Here are the three steps to the nebulizer session:

  1. PREPARING THE REQUIRED MATERIAL
  2. THE INHALATION PROCESS ITSELF
  3. GATHERING THE USED MATERIAL
Nebulizer use of 714X as an adjuvant to the perinodular injection may be added only after a first cycle of perinodular injections is completed. This additional therapy is done twelve hours after the perinodular injection (no matter what time the injection was performed in the morning, afternoon or evening).






Preparing the material
Although the nebulizer session is quite simple to do, it does require the appropriate 714X product. One must have on hand:

  1. 714X nebulizer product specifically designed for use in a nebulizer.
    714X for nebulizer use CANNOT be injected. 714X for use in perinodular injections CANNOT be used in a nebulizer.

    714X for nebulizer use is packaged in boxes containing seven 2 ml single dose ampoules. Each nebulizer use requires one ampoule. Each ampoule is scored and easily breakable. A 21-day treatment requires three boxes of product.
  2. The medical device known as a nebulizer must produce droplets equal to or smaller than 5 microns. Such apparatus may be purchased or rented from medical supply facilities. The nebulizer transforms 714X placed into the nebulizer?s small cup into a fine mist. The mist produced is then inhaled through a mouthpiece thereby introducing the active product into the bronchial cavity.
  3. A solid clean table situated close to an electrical outlet.
  4. Tissue paper (Kleenex) or paper towels.
  5. A glass jar to discard the broken ampoules.
The inhalation process
STEP 1 : Preparing the nebulizer
Be sure to understand how the nebulizer functions. Place the nebulizer on a sturdy clean table located close to an electrical outlet. Insure that the nebulizer is well plugged into the electrical outlet.


STEP 2 : Sterilising the mouthpiece
Remove the plastic mouthpiece that will be utilised to inhale the product. Clean the mouthpiece with 94 % alcohol using some cotton balls.


STEP 3 : Fill the nebulizer with water
Fill the nebulizer where indicated with tap water (or bottled water if the tap water is too mineralized). Do not overfill or under fill. Bring the water to the level indicated in the nebulizer.


STEP 4 : Fill the cup with 714X
Remove from the nebulizer the small cup which will be used to store the content of the 714X ampoule. Remove one ampoule from the box of 714X ampoules. Hold the ampoule upright with the left hand (for right-handed people and vice versa for left-handed people). Lightly tap the ampoule to allow the product trapped in the upper part of the ampoule to descend to the bottom part of the ampoule.

With the right hand (for right-handed people, vice versa for left-handed people), using a paper towel, break the ampoule at the scored line. The top of the ampoule must be removed.

Empty the content of the ampoule into the small cup by lightly taping the bottom of the ampoule. Insert the cup into the appropriate area in the nebulizer.


STEP 5:Verify the working condition of the nebulizer
Install the mouthpiece on the nebulizer. Turn the nebulizer on and verify that mist flows from the mouthpiece. Once the verification has been completed, turn the machine off to preserve the product.


STEP 6 : Begin the inhalation process
Do not pick up the nebulizer. The nebulizer must remain level on a table to be functional. Place the sterilised mouthpiece in the mouth and close the mouth.


STEP 7 : Inhale deeply and exhale slowly
Start the nebulizer. Take a deep breath. Swallow and then exhale slowly by the nose keeping the mouth shut. (Stop the nebulizer when exhaling in order to avoid wasting product.)

Continue to inhale deeply, swallow and slowly exhale through the nose until all the product in the small cup has been used. Some crystals or whitish powder like substance may remain in the bottom of the small cup. According to the depth of breaths taken and the type of nebulizer used, the product may be inhaled in anywhere from five to thirty breaths. Some people may be able to take very deep breaths while others cannot. The number of breaths taken is irrelevant as long as all the product is inhaled.


STEP 8 : Cleaning
Once the inhalation session is over, unplug the nebulizer, empty the water, clean and dry the small cup in preparation for the next session. Store the nebulizer in its case.


Some practical hints:

  1. Occasionally some people may experience a slight prickling or burning sensation in the chest or bronchial area. This feeling will pass without any danger to the patient and only indicates that the product is being well absorbed by the nodes of the respiratory tract.

  2. Be sure to use only 714X product specifically designed for nebulizer use (packaged in 2 ml ampoules).



Gathering the used material
714X ampoules for nebulizer use can only be used once. As a precautionary measure, the ampoules as well as any debris from breaking the ampoules should be stored in a glass jar which can be hermetically sealed. This step is suggested to minimise any risks of accidents for the individuals handling domestic waste.

Be sure to keep broken ampoules out of the reach of children.